Vank Cathedral was one of the first churches to be established in the city's Jolfa district by Armenian deportees settled by Shah Abbas I after the Ottoman War of 1603-1605, During the reign of Shah Abbas, the Safavid king, his sagacious policies caused a sizable number of Armenians from Armenia and Azarbaijan to transfer and settle in Esfahan and other regions of Iran. A place called Jolfa was built at the banks of the Zayande-rud River in Esfahan and became the residence of these migrating people. Consequently, churches were erected in that town. Meanwhile, after a short lapse of time, some Armenians moved to Gilan and some resided in Shiraz, Isfahan.Iran.